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Advanced information on the effects of cannabinoids and the endocannabinoid system

Cannabinoid receptors in human body

Cannabinoid receptors - CB1 and CB2

What are cannabinoid receptors? Throughout the world, cannabis has been used recreationally and medicinally for thousands of years. However, it was not until the 1960s that the psychoactive element of cannabis, tetrahydrocannabinol (THC) cannabinoid, was discovered and isolated. Twenty years later, scientists began to understand how THC interacted with the body to produce the "high". In short, cannabinoids bind to an intricate system of receptors in the human body and produce various effects. This is one of the main mechanisms of the endocannabinoid system. So far, the ...

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explanation of cbda thca

CBDa & THCa

What are CBDA and THCA? Research on the medical application of cannabis has made many advances in recent years and the benefits, both medicinal and therapeutic, of cannabinoids such as CBD and THC have been demonstrated. However, these compounds would not exist without their acidic precursors: CBD and THCA. All cannabinoids derived from cannabis and hemp come from the same "mother" compound: CBDG. Through various enzymatic reactions that occur in plant trichomes, CBGA is converted into CBDA, THCA and so on. The proportions of these compounds can vary ...

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how works endocannabinoid system

The Endocannabinoid System

What is the Endocannabinoid System? The endocannabinoid system was discovered while conducting research on how THC interacts with our bodies. Scientists identified a complicated and intricate cellular signaling system that could be found in numerous locations in the human body that they called the endocannabinoid system, or ECS, and proceeded to investigate its function and purpose. Nearly 20 years later, our understanding of ECS is much greater, but there is still much more to discover. Research has revealed that ECS has a direct relationship with the regulation of the following processes: Sleeping Humor ...

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cannabis entourage effect

The Entourage Effect

What is the Entourage Effect? The Entourage Effect was a term coined in 1998 by two Israeli scientists who discovered that there was a difference in the way cannabinoids interacted with our body depending on the amount of fatty acids present. This discovery has led us to realize that each of the more than 400 compounds found in the cannabis plant affects us differently and that, when they all work together, they produce a much more powerful effect than when they are applied separately. The best known process is the ...

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